NOT KNOWN FACTS ABOUT WHERE TO PHENOBARBITAL

Monitor Closely (one)phenobarbital will minimize the extent or result of fentanyl transmucosal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Coadministration of fentanyl with CYP3A4 inducers may lead into a lessen in fentanyl plasma concentrations, lack of efficacy or, perhaps, advancement of a withdrawal